Results 191 to 200 of about 72,470 (313)

Ostwald Process Intensification by Catalytic Oxidation of Nitric Oxide. [PDF]

ACS Omega
Gopakumar J, Myrstad R, Bo Rresen Anda R, Øien H, Enger BRC, Waller D, Ro Nning M.   +6 more
europepmc   +1 more source

Process intensification of atorvastatin calcium crystallization for target polymorph development via continuous combined cooling and antisolvent crystallization using an oscillatory baffled crystallizer. [PDF]

Int J Pharm, 2022
Kshirsagar S, Lakshmi Ramana Susarla N, Ramakrishnan S, Nagy ZK.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Process Intensification at the Nanoscale: Embedding SiC in Zeolites for Energy-Efficient Catalysis. [PDF]

ACS Omega
Young AF, de Souza JT, Costa AMLM, Romano PN, García-Martínez J, de Almeida JMAR.   +5 more
europepmc   +1 more source

Process intensification of continuous-flow seATRP by a sonicated multi-reactor setup.

React Chem Eng, 2023
Zhang S, Junkers T, Kuhn S.
europepmc   +1 more source

A new reactor for process intensification involving the simultaneous application of adjustable ultrasound and microwave radiation. [PDF]

Ultrason Sonochem, 2021
Călinescu I, Vinatoru M, Ghimpețeanu D, Lavric V, Mason TJ.   +4 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using <i>Drosophila</i> S2 Cells. [PDF]

Eng Life Sci
Göbel S, Mayerlen L, Eiser IY, Fichtmueller L, Clements D, Reichl U, Genzel Y, Lehrer A.   +7 more
europepmc   +1 more source

Ultrasound-assisted solution crystallization of fotagliptin benzoate: Process intensification and crystal product optimization. [PDF]

Ultrason Sonochem, 2021
Fang L, Gao Z, Wu S, Jia S, Wang J, Rohani S, Gong J.   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source