Results 71 to 80 of about 323,824 (292)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Recent Progress in High‐Entropy Alloy Electrocatalysts for Hydrogen Evolution Reaction

open access: yesAdvanced Materials Interfaces
High‐entropy alloys (HEAs) materials, as promising nanomaterials, have garnered significant attention from researchers due to their excellent performance in the field of hydrogen evolution reaction (HER). The four core effects of HEAs, including the high‐
Qian Wang   +10 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Camelids and sustainable development [PDF]

open access: yes, 2015
Face to the global changes and new climatic constraints, the camel farming is confronted to new challenges, first to contribute to the “livestock revolution” (for reaching the requirements of a growing human population), especially in remote places of ...
Faye, Bernard
core  

Hybridation of Bayesian networks and evolutionary algorithms for multi-objective optimization in an integrated product design and project management context [PDF]

open access: yes, 2010
A better integration of preliminary product design and project management processes at early steps of system design is nowadays a key industrial issue.
Baron, Claude   +3 more
core   +4 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Assessment of a gas-solid vortex reactor for SO2/NOx adsorption from flue gas [PDF]

open access: yes, 2013
The feasibility of performing the SO2/NOx adsorption process in a gas-solid vortex reactor (GSVR) is examined and compared with the more traditional riser technology.
Ashcraft, Robert   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Characteristics of feeding and breeding practices for intensification of smallholder dairy systems in the Kenya highlands [PDF]

open access: yes
This study aimed at better understanding of the characteristics of feeding and breeding practices smallholder farmers adopt in intensifying their dairy production.
Bebe, B.O., Thorpe, W., Udo, H.M.J.
core   +2 more sources

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