Results 121 to 130 of about 6,996,748 (368)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

THE TASKS OF IMPROVING THE MANAGEMENT SYSTEM OF PROGRAMMES AND PROJECTS IMPLEMENTATION IN MUNICIPAL ADMINISTRATIONS

open access: yesВестник университета, 2019
In the article problems of control systems of municipal authorities are considered. Problems of improvement of control systems of processes of implementation of programs and projects of development of business in administrations of municipal educations ...
R. Mamedov
doaj  

Management of processes of electrochemical dimensional processing

open access: yesIOP Conference Series: Materials Science and Engineering, 2017
© Published under licence by IOP Publishing Ltd. In different industries a lot high-precision parts are produced from hard-processed scarce materials. Forming such details can only be acting during non-contact processing, or a minimum of effort, and doable by the use, for example, of electro-chemical processing.
Z B Sadykov, A R Zakirova, I D Akhmetov
openaire   +3 more sources

Towards a Unifying Process Framework for Services Knowledge Management [PDF]

open access: yes, 2010
Activities concerned with the design, planning and execution of services are becoming increasingly complex. This is due to the involvement of many different stakeholders, the complexity of the service systems themselves, and the dynamic nature of their ...
Ferreira Pires, Luis   +2 more
core   +2 more sources

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Life Cycle Assessment as a Tool of Environmental Safety in Car Recycling

open access: yesCommunications, 2008
Numerous and wide-ranging initiatives are being pursued all over the world today to help pass on a sound natural environment to future generations. Automotive production is one of Slovakian leading industries. Because of urgent priority on protecting the
Milan Majernik   +2 more
doaj   +1 more source

SoaDssPm: A new Service-Oriented Architecture of the decision support system for the Project Management [PDF]

open access: yesEconomics & Strategic Management of Business Process (ESMB) vol 1; pp. 6-10, 2013, 2014
This paper presents an architecture for the Project Management, which is defined using the concepts behind ServiceOriented and Decision Support System. The framework described, denominated as SoaDssPm, represents the following: a coherent solution to the problem of control Project Management the existing gap between the real execution of Project ...
arxiv  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

A Service-Oriented Tool-Chain for Model-Based Systems Engineering of Aero-Engines

open access: yesIEEE Access, 2018
This paper proposes a service-oriented tool-chain with an emphasis on domain-specific views, simulation automation, and process management to support model-based system engineering of aero-engines.
Jinzhi Lu   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy