Results 121 to 130 of about 7,741,332 (274)
Development of an integrated and comprehensive clinical trial process management system. [PDF]
BMC Med Inform Decis Mak, 2023 Shen L +5 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
A new approach in Business Process Management [PDF]
The new wave of BPM (Business Process Management) is not Business Process Reenginering, enterprise application integration, workflow management or another packaged application – it's the synthesis and extension of all these technologies and techniques ...
Hurbean, Luminita
core +1 more source
Interaction-driven definition of e-business processes [PDF]
, 2002 Business-to-business interaction (B2Bi) is the next step for corporate IT [1]. Business relationships become increasingly dynamic, and new requirements emerge for data and process management.
Piccinelli, G., Zirpins, C.
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Retracted: Application of PDCA Process Management in Day Operation Ward and the Influence of Nursing Quality and Safety. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Personalized Recommendation in a Retail Platform Under the Hybrid Selling Mode
Journal of Theoretical and Applied Electronic Commerce ResearchRetail platforms have widely implemented recommender systems to provide personalized recommendations to consumers, influencing sales significantly. However, under the hybrid selling mode where platforms offer both their products and third-party sellers ...
Wei Wang, Xinyu Han, Yuqing Ma, Gang Li
doaj +1 more source
Process Management of Intussusception in Children: A Retrospective Analysis in China. [PDF]
Pediatr Emerg Care, 2022 Sun Z, Song G, Lian D, Zhang Q, Dong L.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source