Results 41 to 50 of about 2,539,278 (266)

An Integrated Process-Related Risk Management Approach to Proactive Threat and Opportunity Handling: A Framework and Rule Language

open access: yes, 2018
Managing risk in business processes has been a subject of active research in the past few years. The current uncertain global business environment especially requires organizations to adopt more effective risk management approaches that properly cope ...
Lee, J   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Business Process Management with Social Software Systems – A New Paradigm for Work Organisation

open access: yes, 2009
Business process management systems are systems aimed to support the management of business processes in organizations. In recent years social software has emerged as all alternative approach for production and work management. In this paper, we contrast
Petia Wohed   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Change-driven process management: exploring a new process paradigm adaptable to societal changes

open access: yes
PurposeProcess management principles are challenging owing to the increasing need for sustainable operations. The demand for rapid deliveries implies accelerated changes and increased flexibility.
Fundin, Anders,   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Culture in business process management: a literature review

open access: yes, 2011
PurposeBusiness process management (BPM) is a management approach that developed with a strong focus on the adoption of information technology (IT). However, there is a growing awareness that BPM requires a holistic organizational perspective especially ...
Theresa Sinnl   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Cognitive Computing: What's in for Business Process Management?

open access: yes, 2022
S.419-428Cognitive Computing promises to fundamentally transform corporate information processing and problem solving. Building on latest advances in cognitive, data, and computer science, Cognitive Computing aims to deliver autonomous reasoning and ...
Muehlen, Michael zur   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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