Results 51 to 60 of about 2,539,278 (266)

Macro-process 01 Knowledge Management [PDF]

Process Manual. Diagrammed flows of activities, sub processes and processes that make up Macroprocess 1 "Knowledge Management".Macroprocess 1 Knowledge Management aims to “Guarantee the continuous collaborative creation, effective coordination and shared
Organizational Design Division
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Harry Weese : humanism and tradition (Process Achitecture No. 11)

, 1979
164hlm.;bib ...
Process Architecture
core  

Development of market-oriented strategies through cross-functional integration in the context of the food and beverage industry

, 2020
PurposeThe objective of this study is to analyze how cross-functional integration contributes to the development of market-oriented strategies in the context of food and beverage manufacturers in Latin America.Design/methodology/approachA multi-case ...
Murillo-Oviedo, Ana Beatriz,, Piato, Éderson Luiz,, Hilletofth, Per,, Piato, Éderson Luiz, Murillo Oviedo, Ana B.,, Murillo Oviedo, Ana Beatriz, Pimenta, Márcio Lopes, Hilletofth, Per, Pimenta, Marcio Lopes,, Pimenta, Marcio L.,, Piato, Éderson L.,   +10 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Design For Gathering People: Seven Planning Process

, 1993
152 hlm.; ill.; 30 ...
PROCESS ARCHITECTURE 113
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Impact of Process Safety on Productivity and the Bottom Line [PDF]

, 1998
PresentationHow does process safety impact productivity and the bottom-line? A total safety process. Kvaerner utilizes aspects of Process Safety Management to control the safety quality of its process design. PSM also drives many aspects of construction,
Gaylon Fortune
core  

Modelling flow for surgery management process

, 2009
This research uses information quality theory, modifies a technique known as IDEF0 and adapts another technique referred to as design structured Matrix in order to map the information flow within the surgery management process. (in Chinese Language)
Al-Hakim, Latif
core   +1 more source