Results 71 to 80 of about 31,124,721 (333)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Reengineering of production processes and its impact on the financial situation and business performance of the company

Engineering Management in Production and Services, 2019
The current competitive environment is only favourable to those companies that can cope with changes and use them to their advantage. The innovation of business processes is required to improve financial performance. Scientific works have not yet offered
Sujová Andrea, Simanová Ľubica, Marcineková Katarína   +2 more
doaj   +1 more source

Next-generation Process Management with ADEPT2 [PDF]

, 2007
Short time-to-market, easy adaptation to changes in business environment, and robustness of processes are key requirements in today’s business world. In the IT area of Business Process Management (BPM), solutions claim to satisfy these new demands, but ...
Acker, Hilmar, Dadam, Peter, Göser, Kevin, Jurisch, Martin, Kreher, Ulrich, Lauer, Markus, Reichert, Manfred, Rinderle-Ma, Stefanie   +7 more
core   +3 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

The Decomposition Process of Insurance Operations

Foundations of Management, 2014
This study sets out an original concept of the decomposition process of insurance operations. The first part of the paper presents the concept of the process, the process-based approach and process management.
Gąsiorkiewicz Lech
doaj   +1 more source

Elastic Business Process Management: State of the Art and Open Challenges for BPM in the Cloud [PDF]

, 2014
With the advent of cloud computing, organizations are nowadays able to react rapidly to changing demands for computational resources. Not only individual applications can be hosted on virtual cloud infrastructures, but also complete business processes ...
Hoenisch, Philipp, Janiesch, Christian, Schulte, Stefan, Venugopal, Srikumar, Weber, Ingo   +4 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Discussion paper: implications for the further development of the successfully in emergency medicine implemented AUD2IT-algorithm

Frontiers in Digital Health
The AUD2IT-algorithm is a tool to structure the data, which is collected during an emergency treatment. The goal is on the one hand to structure the documentation of the data and on the other hand to give a standardised data structure for the report ...
Christopher Przestrzelski, Antonina Jakob, Clemens Jakob, Felix R. Hoffmann   +3 more
doaj   +1 more source

Model for implementing a reengineering solution of the production process in a printing house

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
The main objective of the present paper is to highlight the importance and impact of the concept of reengineering, both by identifying certain opportunities to improve the performance of Romanian printing companies and some strategies of total redesign ...
Epure Dănuţ-Tiberius, Micu Adrian, Susanu Irina, Micu Angela-Eliza   +3 more
doaj   +1 more source