Results 141 to 150 of about 4,031,943 (267)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Construction of an Interpretive Structural Model-Analytic Network Process model for preschool children's drowning risk factors based on the Haddon matrix. [PDF]

Front Public Health
Ma F, Luo D, Liu H, Zhao G.
europepmc   +1 more source

Models of transition processes

Papers of the Regional Science Association, 1977
W. ISARD, P. LIOSSATOS
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Economic evaluation of a digital symptom checker for endometriosis using a Markov decision process model. [PDF]

NPJ Digit Med
Xu Y, Prentice C, Torres-Rueda S, Meczner A, Multmeier J, Wickham A, Kelly L, Klepchukova A, Stsefanovich H, Zhaunova L.   +9 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Compassionate Extracorporeal Membrane Oxygenation Discontinuation: A Narrative Review and Practical Process Model for Reliable End-of-Life Care. [PDF]

Healthcare (Basel)
Hubel K, Reddy R, Khan A, Pak J, Sher N.
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Determinants of protective behaviors against COVID-19 among young adults: application of the extended parallel process model. [PDF]

Sci Rep
Mahmoodi H, Bagheri S, Lotfollah A, Setayesh A, Hossaini A.   +4 more
europepmc   +1 more source

Interactive Process Models.

, 2004
Contemporary business process systems are built to automate routine procedures. Automation demands well-understood domains, repetitive processes, clear organisational roles, an established terminology, and predefined plans. Knowledge work is not like that.
openaire   +1 more source