Results 111 to 120 of about 13,364,467 (259)

Scenario-based process modeling with GRETA

open access: yes, 2010
Designing understandable business process models is one of the key factors to successful business process management. Current modeling practices advocate the use of block-oriented concepts and subprocesses to structure complex process models.
La Rosa, M., Fahland, D., Weidlich, M.
core  

Analysis and Modeling of Design Problems in the Context of Random Technological Changes

open access: yesTechnologia i Automatyzacja Montażu
This article presents a novel approach to analyzing and modeling design challenges, addressing the impact of dynamically changing technologies. Based on extensive research and industrial experience, the author developed hypotheses defining ...
Paweł Knast
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An Experiment to Analyze the Use of Process Modeling Guidelines to Create High-Quality Process Models [PDF]

open access: yes, 2019
Process modeling guidelines are an essential tool to help process modelers to create models that are correct and easy to understand. Many guidelines have been proposed in the literature, but there is little empirical evidence to which extent guidelines ...
Fantinato, Marcelo   +5 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Critical success factors of business process modeling [PDF]

open access: yes, 2007
This Paper describes the derivation and validation of a process modeling critical success factor ...
Gable, Guy G.   +2 more
core  

Point-process modeling of secondary crashes. [PDF]

open access: yesPLoS One, 2023
Motagi S   +4 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Agarose Cryogels: Production Process Modeling and Structural Characterization. [PDF]

open access: yesGels, 2023
Mancino R   +8 more
europepmc   +1 more source

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