Results 121 to 130 of about 39,470,906 (335)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

High-Level Process Modeling—An Experimental Investigation of the Cognitive Effectiveness of Process Landscape Diagrams

open access: yesMathematics
Unlike business process diagrams, where ISO/IEC 19510 (BPMN 2.0) prevails, high-level process landscape diagrams are being designed using a variety of standard- or semi-standard-based notations. Consequently, landscape diagrams differ among organizations,
Gregor Polančič, Katja Kous
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The introduction of digital twins into the production cycles of biotech companies in the context of the Pharma 4.0 concept

open access: yesИнтеллект. Инновации. Инвестиции
Digital transformation allows you to achieve a competitive advantage in the market while reducing costs and expenses, but at the same time improving quality, which is a cornerstone aspect in the biotechnology industry.
L. V. Lapidus, A. A. Kravchenko
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Model-Based Predictive Adaptive Control of Pulp and Paper Mill Processes

open access: bronze, 2006
Jyunji Mizuki   +4 more
openalex   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Parametric study and process modeling for metronidazole removal by rhombic dodecahedron ZIF-67 crystals. [PDF]

open access: yesSci Rep, 2023
Mazloomi S   +8 more
europepmc   +1 more source

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