Results 51 to 60 of about 42,397,765 (329)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Land Subsidence and Ground Fissures in Beijing Capital International Airport (BCIA): Evidence from Quasi-PS InSAR Analysis

Remote Sensing, 2019
Land subsidence is a global environmental geological hazard caused by natural or human activities. The high spatial resolution and continuous time coverage of interferometric synthetic aperture radar (InSAR) time series analysis techniques provide data ...
Mingliang Gao, Huili Gong, Xiaojuan Li, Beibei Chen, Chaofan Zhou, Min Shi, Lin Guo, Zheng Chen, Zhongyun Ni, Guangyao Duan   +9 more
doaj   +1 more source

Non-invasive MRI quantification of cerebrospinal fluid dynamics in amyotrophic lateral sclerosis patients

Fluids and Barriers of the CNS, 2020
Background Developing novel therapeutic agents to treat amyotrophic lateral sclerosis (ALS) has been difficult due to multifactorial pathophysiologic processes at work. Intrathecal drug administration shows promise due to close proximity of cerebrospinal
Lucas R. Sass, Mohammadreza Khani, Jacob Romm, Marianne Schmid Daners, Kyle McCain, Tavara Freeman, Gregory T. Carter, Douglas L. Weeks, Brian Petersen, Jason Aldred, Dena Wingett, Bryn A. Martin   +11 more
doaj   +1 more source

Manufacturing Process Modeling and Simulation [PDF]

, 2008
This paper presents a methodology to be employed in the whole process design phase including first and second processing. This methodology consists of a set of steps which are characterised by an independent model.
DANTAN, Jean-Yves, MARTIN, Patrick, MIHALUTA, Marius   +2 more
core   +4 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Diffusion process modeling by using fractional-order models

Applied Mathematics and Computation, 2015
This paper deals with a concept and description of a RC network as an electro-analog model of diffusion process which enables to simulate heat dissipation under different initial and boundary conditions. It is based on well-known analogy between heat and
D. Sierociuk, T. Skovranek, M. Macias, I. Podlubny, I. Petráš, A. Dzieliński, Pawel Ziubinski   +6 more
semanticscholar   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The uses of process modeling : a framework for understanding modeling formalisms [PDF]

, 1992
There is wide-spread recognition of the urgent need to improve software processes in order to improve the performance of software organizations. Process models are essential in achieving understanding and visibility of processes and are important for ...
Kleppinger, William H., Osterweil, Leon J., Tamanaha, Doris Y.   +2 more
core  

Point process modeling for directed interaction networks

, 2012
Network data often take the form of repeated interactions between senders and receivers tabulated over time. A primary question to ask of such data is which traits and behaviors are predictive of interaction.
Andersen, Andersen, Anderson, Aral, Boyd, Breslow, Broström, Butts, Cook, Cox, Cox, Eagle, Efron, Fleming, Fowler, Goldenberg, Haberman, Jackson, Kolaczyk, Lenglart, Martinussen, McCullagh, Mckenzie, McPherson, Nocedal, Papachristos, Rebolledo, Snijders, Sundaresan, Tapia, Therneau, Tyler, Vu, Vu, Wong, Zhou   +35 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source