Results 71 to 80 of about 13,364,467 (259)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Carbon Impact Mitigation of the Iron Ore Direct Reduction Process through Computer-Aided Optimization and Design Changes

Metals, 2020
The steel industry is known to have one of the highest environmental impacts on the industrial sector, especially in terms of CO2 emissions. The so-called direct reduction route, which makes use of reformed natural gas along with top gas recycling to ...
Rami Béchara, Hamzeh Hamadeh, Olivier Mirgaux, Fabrice Patisson   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Impact of Novel and Emerging Nonthermal Technologies on the Functionality and Digestibility of Poultry-Derived Proteins

Foods
Poultry meat and eggs are high-quality protein sources, but thermal processing alters their nutritional and functional attributes. Emerging non-thermal and novel processing methods, such as high-pressure processing, ultrasound, pulsed electric fields ...
Anjana Rajendran, Pilli Pavan Sreehitha, Pavithrakumar Thennarasu, Mariam Shibu Thunjath, Jeyan Arthur Moses   +4 more
doaj   +1 more source

Business Process Management in Higher Education. The Case of Students of Logistics

Problemy Zarządzania, 2017
The article contains an introduction to BPM and presents the examples of BPM deployment in high schools. The main part of the article contains the key preparation and realization stages of BPM course for students of logistics at Maria Curie-Skłodowska ...
Łukasz Wiechetek, Marek Mędrek, Jarosław Banaś   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Author Correction: Assessment of natural groundwater reserve of a morphodynamic system using an information-based model in a part of Ganga basin, Northern India

Scientific Reports, 2022
N. C. Mondal, V. Ajaykumar
doaj   +1 more source

Selkov’s Dynamic System of Fractional Variable Order with Non-Constant Coefficients

Mathematics
This article uses an approach based on the triad model–algorithm–program. The model is a nonlinear dynamic Selkov system with non-constant coefficients and fractional derivatives of the Gerasimov–Caputo type.
Roman Parovik
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Algorithms for Solving Ordinary Differential Equations Based on Orthogonal Polynomial Neural Networks

Algorithms
This article proposes single-layer neural network algorithms for solving second-order ordinary differential equations, based on the principles of functional connection.
Roman Parovik
doaj   +1 more source