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Modeling the object-oriented software process: OPEN and the unified process [PDF]
, 1999 A short introduction to software process modeling is presented, particularly object-oriented modeling. Two major industrial process models are discussed: the OPEN model and the Unified Process model.
Aksit, Mehmet +2 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The chapter describes two categories of process-based models, namely, hydrological and socio-hydrological models. It starts with an explanation of the modelling chain from climate drivers via process-based models to identification of hydrological and socio-hydrological drought characteristics.
Van Lanen, Henny A.J. +3 more
openaire +5 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Dynamic Modeling of the Solar Field in Parabolic Trough Solar Power Plants
Energies, 2015 Parabolic trough solar power plants use a thermal fluid to transfer thermal energy from solar radiation to a water-steam Rankine cycle in order to drive a turbine that, coupled to an electrical generator, produces electricity.
Lourdes A. Barcia +6 more
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Heat Transfer Fluid Temperature Control in a Thermoelectric Solar Power Plant
Energies, 2017 Thermoelectric solar plants transform solar energy into electricity. Unlike photovoltaic plants, the sun’s energy heats a fluid (heat transfer fluid (HTF)) and this, in turn, exchanges its energy, generating steam.
Lourdes A. Barcia +4 more
doaj +1 more source
Decision Support Systems, 1993 Abstract While other work in model management has looked at models as static objects to be administered in database-like fashion, we emphasize the central role of process knowledge in model construction, usage, and maintenance. We claim that tools are needed to collaboratively elicit knowledge, to represent it conceptually, and to maintain its ...
Matthias Jarke, Vasant Dhar
openaire +2 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source