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The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Monitoring the development process with Eclipse [PDF]
Monitoring the development process is a complex task due to the amount of resources required (i.e. time and money), moreover the correctness of collected data is not guaranteed if the required tasks are performed manually. This paper describes an extension of the Eclipse IDE environment to allow developers to collect data regarding the development ...
Alberto Sillitti +3 more
openaire +3 more sources
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Transaction processing monitors
Communications of the ACM, 1990A transaction processing (TP) application is a program that performs an administrative function by accessing a shared database on behalf of an on-line user. A TP system is an integrated set of products that supports TP applications. These products include both hardware, such as processors, memories, disks and communications controllers, and software ...
openaire +2 more sources
Monitoring of Microalgal Processes
2015Process monitoring, which can be defined as the measurement of process variables with the smallest possible delay, is combined with process models to form the basis for successful process control. Minimizing the measurement delay leads inevitably to employing online, in situ sensors where possible, preferably using noninvasive measurement methods with ...
Ivo, Havlik +2 more
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Modeling and Monitoring of Dynamic Processes
IEEE Transactions on Neural Networks and Learning Systems, 2012In this paper, a new online monitoring approach is proposed for handling the dynamic problem in industrial batch processes. Compared to conventional methods, its contributions are as follows: (1) multimodes are separated correctly since the cross-mode correlations are considered and the common information is extracted; (2) the expensive computing load ...
Yingwei Zhang +3 more
openaire +2 more sources
2010
In this chapter, we introduce the TEKNE Metrics Framework that performs services to monitor business processes. This framework was designed to support the prescription and explanation of these processes. TEKNE’s most innovative contribution is managing data expressed in declarative form.
E. Damiani +3 more
openaire +1 more source
In this chapter, we introduce the TEKNE Metrics Framework that performs services to monitor business processes. This framework was designed to support the prescription and explanation of these processes. TEKNE’s most innovative contribution is managing data expressed in declarative form.
E. Damiani +3 more
openaire +1 more source

