Results 221 to 230 of about 257,671 (312)

Proposal of a Model-Driven Ontology for Product Development Process Interoperability and Information Sharing

, 2016
Anderson Luis Szejka, Osíris Canciglieri, Eduardo de Freitas Rocha Loures, Hervé Panetto, Alexis Aubry   +4 more
openalex   +2 more sources

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

Assessing the effectiveness of ontology-grounded AI term extraction using OntoGPT for environmental evidence synthesis. [PDF]

Environ Evid
Hodgson RY, Robinson SA, Boutin AC, Chan FK, Bennett JR, Buxton RT, Caufield JH, Hanna DEL, Alamenciak T.   +8 more
europepmc   +1 more source

Dual-Aspect Quantum Theory: An Ontological Framework Unifying Physical Processes and Phenomenal Consciousness

Oliveira, Gustavo
openalex   +1 more source

Toward an ontological formalisation for a software functional size measurement method's application process: The FPA case. [PDF]

, 2004
Evariste Valéry Bévo Wandji, Ghislain Lévesque, Jean-Guy Meunier   +2 more
openalex  

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Integrating text mining and knowledge graph to enhance biopharmaceutical process optimization. [PDF]

PLoS One
Bhowmik S, Anandakrishnan M, Klein L, Arighi C, Gioioso M, Wu C, Brockmeier A, Vijay-Shanker K, Chen C.   +8 more
europepmc   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

molIEreVIS: exploring and interpreting the evidence behind drug repurposing predictions. [PDF]

Front Bioinform
Alnouri A, Hinterreiter A, Steinparz C, Bajraktari L, Burgstaller-Muehlbacher S, Bauer M, Alanis-Lobato G, Streit M.   +7 more
europepmc   +1 more source