Results 41 to 50 of about 257,671 (312)

Knowledge processes and ontologies

open access: yesIEEE Intelligent Systems, 2001
In this article, we present an approach for ontology-based knowledge management (KM) that includes a tool suite and a methodology for developing ontology-based KM systems. It builds on the distinction between knowledge processes and knowledge metaprocesses, and is illustrated by CHAR (Corporate History AnalyzeR), a KM system for corporate history ...
Staab, Steffen   +3 more
openaire   +2 more sources

Enterprise-Specific Ontology-Driven Process Modelling [PDF]

open access: yes, 2015
Different process models are created within an enterprise by different modelers who use different enterprise terms. This hinders model interoperability and integration. A possible solution is formalizing the vocabulary used within the enterprise in an ontology and put this ontology as bases for constructing process models.
Alkhaldi, Nadejda   +2 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Domain Ontology for Software Requirements Change Management in Global Software Development Environment

open access: yesIEEE Access, 2019
Ontology and its role in both software engineering and knowledge management fields have been widely reported in the literature. Numerous studies have proven the effectiveness of using ontologies to support the process of requirements engineering.
Abeer Abdulaziz Alsanad   +2 more
doaj   +1 more source

Scale in Object and Process Ontologies [PDF]

open access: yes, 2003
Scale is of great importance to the analysis of real world phenomena, be they enduring objects or perduring processes. This paper presents a new perspective on the concept of scale by considering it within two complementary ontological views. The first, called SNAP, recognizes enduring entities or objects, the other, called SPAN, perduring entities or ...
Reitsma, Femke, Bittner, Thomas
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Ontology Update in the Cognitive Model of Ontology Learning

open access: yesITM Web of Conferences, 2016
Ontology has been used in many hot-spot fields, but most ontology construction methods are semiautomatic, and the construction process of ontology is still a tedious and painstaking task.
Zhang De-Hai   +4 more
doaj   +1 more source

Domain Ontologies and the Conversion of Tacit Knowledge in Software Development [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2021
This study presents a proposal to build and analyze a domain ontology as a tool to support the knowledge transfer process in the context of software requirements analysis in the medical/pharmaceutical industry.
Euler Evangelista, Cristiana De Muÿlder
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

THE ANALYSES OF BUSINESS PROCESS CONCEPTUAL MODEL BASED ON BUNGE-WAND-WEBER ONTOLOGY

open access: yesСтатистика и экономика, 2016
This article discusses the Bunge-Wand-Weber representation ontology that is widely used for business process modeling and in object oriented IT development.
Igor G. Fedorov
doaj   +1 more source

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