Results 61 to 70 of about 257,671 (312)

THE PROPOSAL OF AN ONTOLOGY FOR THE RECRUITMENT PROCESS [PDF]

open access: yesOradea Journal of Business and Economics
The paper presents a useful ontology for managing activities within a recruitment company, using Protégé 3.5. A well-designed recruitment ontology must contain clearly defined terms and relationships.
Ana-Maria TEODORESCU
doaj   +1 more source

Information as a Morpho-Ontological Process [PDF]

open access: yesProceedings of the IS4SI 2017 Summit DIGITALISATION FOR A SUSTAINABLE SOCIETY, Gothenburg, Sweden, 12–16 June 2017., 2017
The debate about information is clearly ontological: how do we know what is real? Which is the object of our knowledge? Only after having clarified this point we can start epistemological debates, which at their turn, are part of the ontological perspective (about nature, knowledge, and the world itself, here the vicious circle).
openaire   +3 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

A Domain Ontology for Gait Analysis and Decision Support on Gait-Related Diseases

open access: yesIEEE Access
The complexity of diagnosing and treating gait-related diseases necessitates the existence of a domain ontology that can support intelligent decision-making by gait experts and medical personnel.
Terrance Marthinus, Olawande Daramola
doaj   +1 more source

Ontology-based approach to reuse of business process knowledge

open access: yesInformacijos Mokslai, 2008
The paper proposes an approach to reuse of business process knowledge based on domain engineering, knowledge engineering and ontology-based systems engineering.
Donatas Čiukšys, Albertas Čaplinskas
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The Ontology of Causal Process Theories [PDF]

open access: yesPhilosophia, 2011
There is a widespread belief that the so-called process theories of causation developed by Wesley Salmon and Phil Dowe have given us an original account of what causation really is. In this paper, I show that this is a misconception. The notion of “causal process” does not offer us a new ontological account of causation.
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Home - About - Disclaimer - Privacy