Results 71 to 80 of about 257,671 (312)
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Using Large Language Models for Ontology Development
Engineering ProceedingsThis paper explores the application of Large Language Models (LLMs) for ontology development, focusing specifically on cloud service ontologies. We demonstrate how LLMs can streamline the ontology development process by following a modified Ontology ...
Darko Andročec
doaj +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Ontological modelling of welding processes
IOP Conference Series: Materials Science and Engineering, 2021 Abstract In this work, an ontological model for welding processes is proposed and the need to manage the information and knowledge associated with such complex discipline is justified. First, an overview of the meaning and use of the models for this purpose and the concept of interoperability applied to the information contained in the ...
openaire +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Research on coal mine safety ontology
Gong-kuang zidonghua, 2018 Common ontology languages, construction principles and construction methods were summarized. It was considered that constructing coal mine safety ontology should adopt OWL-DL language and the construction method of cyclic acquisition method or seven-step
SHI Qinfu +4 more
doaj +1 more source
Conjugated Polymer Process Ontology and Experimental Data Repository for Organic Field-Effect Transistors. [PDF]
Chem Mater, 2023 Liu AL +7 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi +4 more
wiley +1 more source
Developing process-base ontology for knowledge management technologies
Iranian Journal of Information Processing & Management, 2018 This paper is an attempt to develop a new ontology for knowledge management (KM) technologies, determining the relationships between these technologies and classification of them. The study applies NOY methodology.
Parvin Hashemi +2 more
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