Results 81 to 90 of about 23,429,950 (320)

LyoPRONTO: an Open-Source Lyophilization Process Optimization Tool

AAPS PharmSciTech, 2019
This work presents a new user-friendly lyophilization simulation and process optimization tool, freely available under the name LyoPRONTO. This tool comprises freezing and primary drying calculators, a design-space generator, and a primary drying ...
Gayathri Shivkumar, Petr Kazarin, A. Strongrich, Alina A. Alexeenko   +3 more
semanticscholar   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

The Complex Effect of Food Matrix Fat Content on Thermal Inactivation of Listeria monocytogenes: Case Study in Emulsion and Gelled Emulsion Model Systems

Frontiers in Microbiology, 2020
Previous studies on the influence of food matrix fat content on thermal inactivation kinetics of food pathogens have shown contradictory results due to the combined influence of fat content and other factors such as composition.
Davy Verheyen, Davy Verheyen, Davy Verheyen, Marlies Govaert, Marlies Govaert, Marlies Govaert, Ti Kian Seow, Jonela Ruvina, Vivek Mukherjee, Maria Baka, Maria Baka, Maria Baka, Torstein Skåra, Jan F. M. Van Impe, Jan F. M. Van Impe, Jan F. M. Van Impe   +15 more
doaj   +1 more source

Bayesian optimization for materials design

, 2015
We introduce Bayesian optimization, a technique developed for optimizing time-consuming engineering simulations and for fitting machine learning models on large datasets.
A Booker, A Forrester, AB Gelman, AIJ Forrester, B Ankenman, BE Stuckman, CE Rasmussen, D Huang, D Huang, David Ginsbourger, Diana M. Negoescu, DR Jones, HJ Kushner, J Bect, J Knowles, J Mockus, J Villemonteix, J Xie, LP Kaelbling, Noel Cressie, PI Frazier, PI Frazier, PI Frazier, R Waeber, RA Howard, RS Sutton, Sethuraman Sankaran, TJ Santner, W Scott   +28 more
core   +1 more source

Certificates of infeasibility via nonsmooth optimization [PDF]

, 2015
An important aspect in the solution process of constraint satisfaction problems is to identify exclusion boxes which are boxes that do not contain feasible points.
Fendl, Hannes, Neumaier, Arnold, Schichl, Hermann   +2 more
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research on an Equivalent Heat Source Model of the AC Arc in the Short Gap of a Copper-Core Cable and a Fire Risk Assessment Method

Sensors
The magnetohydrodynamics (MHD) model of the alternating current (AC) arc is complex, so a simplified equivalent heat source (EHS) model can be used to replace the complex model in studying the AC arc’s thermal characteristics and cable fire risk.
Yu Li, Rencheng Zhang, Kai Yang, Yufan Qi   +3 more
doaj   +1 more source

Adjusting process count on demand for petascale global optimization⋆ [PDF]

, 2011
There are many challenges that need to be met before efficient and reliable computation at the petascale is possible. Many scientific and engineering codes running at the petascale are likely to be memory intensive, which makes thrashing a serious ...
Haftka, Rafael T., Radcliffe, Nicholas R., Sosonkina, Masha, Trosset, Michael W., Watson, Layne T.   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source