Results 121 to 130 of about 16,522,858 (310)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Design For Gathering People: Seven Planning Process

open access: yes, 1993
152 hlm.; ill.; 30 ...
PROCESS ARCHITECTURE 113
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Process Antifoulants for Energy Conservation in the '80's

open access: yes, 1982
Specialty chemical treatments and related services have been used for may years to enhance the efficiency of industrial processes. In particular, this paper relates to the use of proprietary antifoulants and associated technology to inhibit the formation
Freeman, R. F.   +2 more
core  

Identifying the optimum process parameters for ultrasonic cellular disruption of e. coli

open access: yes, 2012
The aim of this work is to identify the optimum process parameters of sonication, manosonication and thermosonication for deactivating E. coli ATCC 25922 in water-based suspension.
Al-Juboori, Raed A., Yusaf, Talal
core   +1 more source

Historical Perspectives on Chemical Process Safety at Texas A&M--Education, Research and Service [PDF]

open access: yes, 1998
PresentationThe Mary Kay O=Connor Process Safety Center was formally established at Texas A&M in 1995. This presentation will outline the activities leading up to the establishment of the Center, and the subsequent activities of the center in the areas ...
Fortune, Gaylon
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Impact of Process Safety on Productivity and the Bottom Line [PDF]

open access: yes, 1998
PresentationHow does process safety impact productivity and the bottom-line? A total safety process. Kvaerner utilizes aspects of Process Safety Management to control the safety quality of its process design. PSM also drives many aspects of construction,
Gaylon Fortune
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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