Results 111 to 120 of about 16,522,858 (310)

On the parameter estimation for an explosive process

open access: yesJournal of the Japan Statistical Society, Japanese Issue, 1986
The author shows the strong consistency of the canonical parameters of a vector ARMA process, or a state space representation, even when the system is unstable. The paper is clear and well written.
openaire   +2 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Harry Weese : humanism and tradition (Process Achitecture No. 11)

open access: yes, 1979
164hlm.;bib ...
Process Architecture
core  

Parameters – Full Issue – Winter 2014 [PDF]

open access: yes, 2014
Asia Pacific: Reassessing China by David Lai, Thomas M. Kane, Timothy L. Thomas, Christopher Bowen Johnston Middle East: Defeating the Islamic State by Huba Wass de Czege, Paul Rexton Kan A War Examined: Gaza 2014 by Eitan Shamir, Eado Hecht, Glenn E ...
Parameters, USAWC, USAWC Parameters
core   +1 more source

Choosing Optimal Parameters in Iterative Processes

open access: yesJournal of Complexity, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Parameters – Full Issue – Summer 2015 [PDF]

open access: yes, 2015
Has the US Lost the Ability to Fight a Major War? by Steven Metz The US Military in Africa by Kristen A. Harkness, Kertsi Larsdotter Threats Within and Without by, Amy Zegart, John R. Deni Toward a Smarter Military by Robert R. Tomes, Everett S.P. Spain,
Parameters, USAWC, USAWC Parameters
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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