Results 91 to 100 of about 16,522,858 (310)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Weld Formation in Laser Hot-Wire Welding of 7075 Aluminum Alloy

open access: yesMetals, 2018
The laser hot-wire welding process was adopted to weld 7075 high-strength aluminum alloy. The influence laws of parameters on the weld formation were analyzed during laser hot-wire welding, and the microstructure characteristics and mechanical properties
Shichun Li, Wei Xu, Gang Xiao, Bing Chen
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Experimental and Numerical Investigation of the Influence of Process Parameters in Incremental Sheet Metal Forming on Residual Stresses

open access: yesJournal of Manufacturing and Materials Processing, 2019
The aim of this study is to analyze the co-relation between the geometrical accuracy of parts formed by single-point incremental forming (SPIF) and the resulting distribution of the residual stresses induced in the material as a function of the different
Fawad Maqbool, Markus Bambach
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evaluating and controlling process variability in micro-injection moulding [PDF]

open access: yes, 2011
Microsystem technologies require relatively strict quality requirements. This is because their functionalities are usually dependent on stringent requirements of dimensions, masses or tolerances. When mass-producing micro-components, e.g.
Alcock, Jeffrey R., Attia, Usama M.
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Research on Correlation between Weld Concavity and Weld Process Parameters in Tailored Blank Laser Welding

open access: yes, 2010
Weld quality control is of great importance in tailored blank laser welding for the purpose of making products at a high quality and high productivity.
Zhao MY(赵明扬)   +5 more
core   +1 more source

Parameters – Full Issue – Winter 2015 [PDF]

open access: yes, 2015
Special Commentary: Rethinking America’s Grand Strategy by Hal Brands The Efficacy of Landpower by Michael Allen Hunzeker, Alexander Lanoszka, Joseph Roger Clark Professionalism and the Volunteer Military by Don M. Snider, Louis G.
Parameters, USAWC, USAWC Parameters
core   +1 more source

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