Results 71 to 80 of about 28,919,767 (317)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Novel Ceramic Clay Automatic Feeding System and Simulation Analysis
CeramicsThis study aims to verify the feasibility and effectiveness of an automatic feeding system in the ceramic clay-forming process. Through a series of clay-forming experiments, the system’s performance under various process parameters was examined ...
Xunchen Liu +6 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
MetalsFiber lasers, the latest laser-cutting technology, are notable for their high process efficiency, cutting precision, and high cutting quality for thin materials.
Laura Cepauskaite, Regita Bendikiene
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
CrystalsUsing finite element simulation and single-variable experimental methods, this study analyzes the variations in the microstructure and hardness of a 304 stainless steel wire during Joule heating fused filament fabrication.
Suli Li +5 more
doaj +1 more source
Journal of Aeronautical Materials, 2019 The influence of the process parameters of SiC ceramics on the processing quality was discussed. The corrosion mechanism of SiC ceramics was analyzed. The corrosion rate and porosity of samples were measured by the method of weight-loss and Archimedes ...
LIU Shanyong +5 more
doaj +1 more source
BNC Biosynthesis with Increased Productivity in a Newly Designed Surface Air-Flow Bioreactor
Applied Sciences, 2020 The application of bacterial cellulose (BNC) could be widely expanded if the production costs were reduced. This study aims to determine factors simultaneously affecting the yield and tensile strength of BNC in a newly designed surface air-flow ...
Izabela Cielecka +2 more
doaj +1 more source
Materials Research Express, 2021 AlCu5MnCdVA alloys had high specific strength, good machining and fatigue properties, outstanding electroplating and excellent corrosion resistance. However, due to wide crystallization temperature range, it is hard to realize sequential solidification ...
Pan Lu +5 more
doaj +1 more source