Implementing a tracking system for confirmatory diagnostic results after positive newborn screening for cystic fibrosis-implications for process quality and patient care. [PDF]
Eur J Pediatr, 2021 Gramer G +8 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Probabilistic Residual Modeling for Sensor-Based Process-Quality Fault Detection in Industrial Systems. [PDF]
Sensors (Basel)Zhang L, Bao X.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Design For Gathering People: Seven Planning Process
, 1993 152 hlm.; ill.; 30 ...
PROCESS ARCHITECTURE 113
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AWJ Cutting Process Quality Modeling and Optimization Based on Footprint Angle. [PDF]
Materials (Basel)Perec A, Kawecka E, Zajac W.
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Clinical process quality of antenatal care in low and middle-income countries: Cross-sectional evidence from 13 countries. [PDF]
PLOS Glob Public HealthKovacs R.
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Value of whole-process quality control management in central sterile supply department nursing practice and nosocomial infection prevention. [PDF]
Pak J Med SciWang F, Zhao N.
europepmc +1 more source