Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Defining the Quality of Business Processes
Heinrich, Robert, Paech, Barbara
openaire +4 more sources
Mechanical cardiopulmonary resuscitation in adult cardiac arrest: setting-specific associations and mediation through resuscitation process quality. [PDF]
Qiao J, Cao RY, Li X.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Procedure-specific pain trajectories and process quality in elective otolaryngology surgery: a single-center cohort study. [PDF]
Wu D +5 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Impact of Data Distribution and Bootstrap Setting on Anomaly Detection Using Isolation Forest in Process Quality Control. [PDF]
Choi H, Jung K.
europepmc +1 more source
Process, quality and challenges of diabetes care in primary care: a study of district health network in Thailand. [PDF]
Somanawat J, Saramunee K, Chanasopon S.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Impact of Process Quality in Early Childhood Education and Care on Socio-Emotional Development: A Meta-Analysis of Longitudinal Studies. [PDF]
Sluiter RMV, Fukkink RG, Fekkes M.
europepmc +1 more source

