Results 91 to 100 of about 14,034,560 (296)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

The evolution of animal-based dietary structure has contributed to the increase of healthcare expenditures in China

open access: yesHumanities & Social Sciences Communications
The trends of diversified diets in China have generated a growing number of nutritional health problems, and healthcare investment is bearing a large burden from the diets, hindering the economic progress of the country and its residents toward affluence.
Yuanyuan Zhu   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Numerical Simulation of Rolling Process and Microstructure Evolution of AM50 Mg Alloy during Hot Rolling Process

open access: yes, 2011
In order to optimize rolling process of AM50 Mg alloy, numerical simulation method is adopted to find reasonable process parameters. And then, the metallograph was viewed to find the microstructure evolution during hot rolling process.
Yao Fu   +21 more
core   +1 more source

Research on the Coupling and Coordination of Land Ecological Security and High-Quality Agricultural Development in the Han River Basin

open access: yesLand
This study aims to investigate the coupling and harmonization between land ecological security (LES) and high-quality agricultural development (HAD) in the Han River Basin (HRB), China, with the objective of promoting harmonious coexistence between ...
Yuelong Su   +3 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Making software process simulation modeling agile and pattern-based

open access: yes, 2022
S.222-227 : Ill., Lit.In many disciplines, simulation is known for its advantageous capability of conducting close-to-reality experiments without affecting the real system or even demanding its availability. In software engineering, however, simulation -
Angkasaputra, N., Pfahl, D.
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Business process simulation survival guide [PDF]

open access: yes, 2015
Simulation provides a flexible approach to analyzing business processes. Through simulation experiments various what if questions can be answered and redesign alternatives can be compared with respect to key performance indicators.
Aalst, van der, W.M.P.   +1 more
core   +1 more source

The Impact of Urban Labor Skill Structure on Industrial Evolution in China and Its Heterogeneity from the Perspective of Cross-Relatedness

open access: yesRedai dili
Industry and occupation are closely interwoven. Focusing solely on industrial structure cannot adequately address regional development challenges. Multifactor cross-relatedness provides a theoretical foundation for understanding the interplay between ...
Zhou Xiaoqi   +3 more
doaj   +1 more source

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