Results 101 to 110 of about 25,592,602 (307)

A dynamical process of several variables

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2018
In the space of ϕ-distributions with values belonging to a Banach space, the process described by the problem of partial differential equation has been considered. Conditions under which the process is dynamic have been given.
V.S. Mokeichev, A.M. Sidorov
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Adaptive soft sensor considering process state in film manufacturing process and identification of critical process variables

open access: yesResults in Chemistry
In the film manufacturing process, process variables, such as temperature and pressure, are measured and controlled to manage the film properties, such as thickness and optical characteristics.
Yuya Shiraki   +5 more
doaj   +1 more source

Air Blowing of Bitumens: Process Variables and Structural Parameters Soufflage des bitumes : variables du procédé et paramètres structuraux

open access: yesOil & Gas Science and Technology, 2006
Effect of process variables viz. air rate, time of air blowing, temperature and catalyst concentration has been investigated and optimised to determine the possibility of making paving grade bitumen from 500°C+ Aghajari Short residue, of appropriate ...
Bahl J. S., Singh H.
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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