Results 131 to 140 of about 15,298,733 (296)
Business process simulation survival guide
, 2015 Simulation provides a flexible approach to analyzing business processes. Through simulation experiments various "what if" questions can be answered and redesign alternatives can be compared with respect to key performance indicators.
Brocke, vom, J. +2 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Jurnal Ilmu LingkunganThe reduction in mangrove areas, which has caused significant erosion along the north coast of North Central Timor Regency, has implied the need for in-depth studies. This research, aimed to determine the spatial distribution of coastal vulnerability and
Ludgardis Ledheng +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Intelligent feature based resource selection and process planning [PDF]
, 2012 Lien vers la version éditeur: https://www.inderscience.com/books/index.php?action=record&rec_id=755&chapNum=3&journalID=1022&year=2010This paper presents an intelligent knowledge-based integrated manufacturing system using the STEP feature-based ...
MARTIN, Patrick +4 more
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Effect of Process Variables and Ingredients on Controlled Protein Network Creation in High-Moisture Plant-Based Meat Alternatives. [PDF]
Foods, 2023 Sengar AS +4 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Optimization of process variables to prepare activated carbon from Noug (Guizotia abyssinica cass.) stalk using response surface methodology. [PDF]
Heliyon, 2023 Yirdaw G, Dessie A, Birhan TA.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source