Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The influence of nursing structure and process variables on patients' outcomes and safety within a High Dependency Unit [PDF]
Outcomes of nursing practice are used to refer to patient outcomes related to, or as a consequence of, nursing care. This research, comprised two studies, extends the investigation about outcomes of nursing practice. Following Donabedian's framework, the
Subirana, Mireia
core
Designs for mixture and process variables applied in tablet formulations
Although there are several methods for the construction of a design for process variables and mixture variables, there are not very many methods which are suitable to combine mixture and process variables in one design.
DUINEVELD, C. A. A. +11 more
core +1 more source
Valorization of Using Agro-Wastes for Levan through Submerged Fermentation and Statistical Optimization of the Process Variables Applying Response Surface Methodology (RSM) Design. [PDF]
Saeed S +4 more
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Nonparametric regression for dependent data in the errors-in-variables problem [PDF]
We consider the nonparametric estimation of the regression functions for dependent data. Suppose that the covariates are observed with additive errors in the data and we employ nonparametric deconvolution kernel techniques to estimate the regression ...
Toshio Honda
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Quality by Design Assisted Optimization and Risk Assessment of Black Cohosh Loaded Ethosomal Gel for Menopause: Investigating Different Formulation and Process Variables. [PDF]
Mohapatra S +6 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Developments in EDM process variables [PDF]
. The electrical discharge machining (EDM) process parameters (both the input and output) are presented. The input variable of EDM presented here are electrical and non-electrical ones.
Mohammad , Yeakub Ali +2 more
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