Results 111 to 120 of about 2,207,660 (295)

Process versus outcome: The sugar window [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2014
Fullerton, David A., Sundt, Thoralf M.
openaire   +4 more sources

Novel process windows, part 1: Boosted micro process technology

open access: yesChimica Oggi, 2011
Novel Process Windows (NPW) is the use of highly intensified, unusual and typically harsh process conditions to boost micro process technology and flow chemistry for the production of high-added value fine chemicals, pharmaceuticals, etc.. It is far from conventional processing and also from "normal" micro processing, and enables "flash chemistry" (1 ...
Volker Hessel, Qi Wang
openaire   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

A Novel Sliding Window PCA-IPF Based Steady-State Detection Framework and Its Industrial Application

open access: yesIEEE Access, 2018
In industrial processes, it is of great significance to carry out steady-state detection (SSD) for effective system modeling, operation optimization, performance evaluation, and process monitoring.
Yalin Wang   +5 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Laser powder bed fusion process optimization of CoCrMo alloy assisted by machine-learning

open access: yesJournal of Materials Research and Technology
Gaussian process regression (GPR) model of machine learning method was employed to identify the optimal process window for high-performance CoCrMo alloy in laser powder bed fusion (LPBF), considering density (≥99%) and surface roughness (≤7 μm) as key ...
Haoqing Li   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Research on cutting mechanics of window bit cutting teeth

open access: yesAdvances in Mechanical Engineering, 2016
According to structural characteristics of dual-effect strong side-cut window bit (hereinafter referred to as window bit) and the theory of metal cutting and the rule of teeth arrangement of window bit, a cutting mechanical model of window bit cutting ...
Chunyan Kong   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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