Results 141 to 150 of about 31,552 (309)
Processability and proficiency: Is there a causal relationship?
, 2019 The objective of this paper is to investigate if the relationship between the Processability Theory, a model for second language acquisition, and proficiency, is causal. The focus will be on attributive and predicative adjectival agreement.
Domenico Saracino, Antonio
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Development of flame-retarded polyamide composition with improved processability [PDF]
, 2013 The article describes influence of reduction of complex flame-retardant (triazine and red phosphorus) and grafted olefin copolymer on performance characteristics of polymeric compositions based on polyamide-6, and also on their extrusion processability ...
Kostsyuchenko, М. А., Revyako, М. М.
core
Processability & Microstructure of Fe-C System via L-PBF
, 2019 Although a variety of ferrous alloys exist in powder metallurgy, the number of approved ferrous alloys in additive manufacturing (AM), especially for structural applications, remains limited.
Nyborg, Lars +3 more
core +1 more source
An in-situ assembled cobweb-like adhesive with high processability
Nature CommunicationsLow temperature tolerant adhesive with high flexibility and adhesion strength is highly desired yet challenging owing to the presence of obvious volume shrinkage, increased brittleness, and reduced transmission of mechanical stress at low temperature ...
Xiaoming Xie +10 more
doaj +1 more source