Results 161 to 170 of about 1,216,096 (316)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Multilevel predictors of ultra-processed food intake in Canadian preschoolers. [PDF]

Commun Med (Lond)
Mousavi S, Chen ZH, Lu Z, Santos S, L'Abbe MR, Azad MB, Mandhane PJ, Moraes TJ, Subbarao P, Turvey SE, Brook JR, Miliku K.   +11 more
europepmc   +1 more source

Improvement of Shelf Life for Space Food Through a Hurdle Approach [PDF]

The processed and prepackaged spaceflight food system is a critical human support system for manned space flights. As missions extend longer and farther from Earth over the next 20 years, strategies to stabilize the nutritional and sensory quality of ...
Cooper, M. R., Douglas, G. L., Froio-Blumsack, D., Mohr, L., Sirmons, T. A., Young, M.   +5 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A perspective of ultra-processed food definitions and classification challenges. [PDF]

Anim Front
Gifford CL.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Ultra-processed food intake and cognitive decline in older adults. [PDF]

Eur J Nutr
Buis C, Nicolaou M, Visser M, Olthof MR, Wijnhoven HAH.   +4 more
europepmc   +1 more source

THE IMPACT OF CHANGING CONSUMER PREFERENCES ON BABY FOOD CONSUMPTION [PDF]

This study examines the relationship between processed baby food consumption, socioeconomic factors, and attitudes and awareness concerning baby food safety and nutrition.
Harris, James Michael
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Ultra-processed food consumption and the risk of overweight and obesity in adolescents: A systematic review and meta-analysis. [PDF]

PLoS One
Aweke MN, Abuhay HW, Limenih MA, Alhur AA, Baykemagn ND, Alemu GG, Tewelgne MF, Yehuala TZ.   +7 more
europepmc   +1 more source