Results 101 to 110 of about 6,728,003 (316)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The process of coopetitive strategy: a case study of microbreweries in Porto Alegre / O processo de estratégia coopetitiva: um estudo de caso de microcervejarias em Porto Alegre

open access: yesRAM. Revista de Administração Mackenzie, 2018
Purpose: The study presents a dynamic and complex procedural experience performed by small microbreweries in a cluster in Porto Alegre, Brazil. Thus, this article aims to establish theoretical propositions about coopetition strategies in this context ...
Jefferson M. Monticelli   +2 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Formation of microelement composition of soils of Stavropol krai under the influence of waterlogging processes

open access: yesНаука. Инновации. Технологии
The object of the study was the hydromorphic soils of the Tashlyansky landscape of ravine forest-steppes, identified in the Stavropol Krai. The radial geochemical structure of differentiation of gross contents of Zn, Cu, Pb and Cd in the profile of ...
T. V. Degtyareva
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Does Foraging or the Avoidance of Predation Determine Habitat Selection by Selective Resident Grazers in the Serengeti Woodlands? A Mixed Strategy with Season

open access: yesAnimals
Savanna systems are characterised by a community of large mammal herbivores with up to 30 species; coexistence is based on resource partitioning. In this paper we analyse the features of the landscape and plant structure which lead herbivores to use ...
Patrick Duncan, Anthony R. E. Sinclair
doaj   +1 more source

Impact of Processing and Analyzing Healthcare Big Data on Cloud Computing Environment by Implementing Hadoop Cluster

open access: diamond, 2016
Sreekanth Rallapalli   +2 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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