Results 131 to 140 of about 684,002 (265)

Hot Deformation Behavior and Processing Maps of Fe-30Mn-0.11C Steel. [PDF]

Materials (Basel), 2018
Kang J, Wang Y, Wang Z, Zhao Y, Peng Y, Wang T.   +5 more
europepmc   +1 more source

Genetic association mapping leveraging Gaussian processes

Journal of Human Genetics
AbstractGaussian processes (GPs) are a powerful and useful approach for modelling nonlinear phenomena in various scientific fields, including genomics and genetics. This review focuses on the application of GPs in genetic association mapping. The aim is to identify genetic variants that alter gene regulation along continuous cellular states at the ...
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Microstructure Evolution, Hot Deformation Behavior and Processing Maps of an FeCrAl Alloy. [PDF]

Materials (Basel)
Fang XQ, Wang JB, Liu SY, Wen JZ, Song HY, Liu HT.   +5 more
europepmc   +1 more source

Hot Deformation Characteristics-Constitutive Equation and Processing Maps-of 21-4N Heat-Resistant Steel. [PDF]

Materials (Basel), 2018
Li Y, Ji H, Li W, Li Y, Pei W, Liu J.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Hot Deformation Behavior and Processing Maps of SiC Nanoparticles and Second Phase Synergistically Reinforced Magnesium Matrix Composites. [PDF]

Nanomaterials (Basel), 2019
Nie K, Zhu Z, Deng K, Wang T, Han J.
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Determining the Hot Workability and Microstructural Evolution of an Fe-Cr-Mo-Mn Steel Using 3D Processing Maps. [PDF]

Materials (Basel)
Dou C, Sun Z, Shen D, Guo N, Liu Z, Cheng L, Liu Y, Tang B.   +7 more
europepmc   +1 more source

Effect of SiC Nanoparticles on Hot Deformation Behavior and Processing Maps of Magnesium Alloy AZ91. [PDF]

Nanomaterials (Basel), 2018
Nie K, Kang X, Deng K, Wang T, Guo Y, Wang H.   +5 more
europepmc   +1 more source