Results 111 to 120 of about 207,528 (316)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
An Educational RISC-V-Based 16-Bit Processor
ChipsThis work introduces a novel custom-designed 16-bit RISC-V processor, intended for educational purposes and for use in low-resource equipment. The implementation, despite providing registers of 16 bits, is based on RV32E RISC-V ISA, but with some key ...
Jecel Mattos de Assumpção +3 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Notes on the design of a barrel shifter for the Warwick pipelined CORDIC processor [PDF]
This document discusses the design decisions made during the design of the barrel shifters used in the floating point adjustment circuitry of the Warwick pipelined CORDIC processor.
Chown, Paul
core
The systolic control ring instruction processor (SCRIP)
, 1990 In this paper we introduce the concept of a systolic control ring instruction processor (SCRIP). A SCRIP is a general purpose systolic computer which combines features of wavefront and systolic data flow for the execution of programs, while also being ...
Megson, G.M., Evans, D.J.
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
IEEE AccessRISC-V is an open-standard Instruction Set Architecture (ISA) that has gained significant popularity in both academia and industry. The adoption of RISC-V is propelled by open-source accessibility, design adaptability, cost efficiency, and an active ...
Daniel Grobe +2 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A CORDIC like processor for computation of arctangent and absolute magnitude of a vector
, 2004 In this paper, we propose a CORDIC like algorithm for computing absolute magnitude of a vector and its corresponding phase angle. It eliminates scale factor compensation step as well as the addition/subtraction operation along the z datapath.
Troya, Alfonso +4 more
core
Digital implementation of the cellular sensor-computers
, 2006 Two different kinds of cellular sensor-processor architectures are used nowadays in various applications. The first is the traditional sensor-processor architecture, where the sensor and the processor arrays are mapped into each other.
Rekeczky, Csaba +3 more
core +1 more source