Results 61 to 70 of about 15,198 (259)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Loop-invariant Code Motion Algorithm Based on Loop Cost Analysis [PDF]

Jisuanji kexue
Loop-invariant code motion(LICM) is a commonly used compilation optimization algorithm for loop structures in programs.By moving the invariant calculations in the loop body to outside the loop,the algorithm reduces the overhead of duplicate calculations ...
JIANG Jun, ZHAI Yanhe, ZENG Zhiheng, GU Yichao, HUANG Liangming
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Framework for Loop Distribution on Limited On-Chip Memory Processors [PDF]

, 2000
This work proposes a framework for analyzing the flow of values and their re-use in loop nests to minimize data traffic under the constraints of limited on-chip memory capacity and dependences. Our analysis first undertakes fusion of possible loop nests intra-procedurally and then performs loop distribution.
Lei Wang, Waibhav Tembe, Santosh Pande
openaire   +1 more source

Speed Regulated Continuous DTC Induction Motor Drive in Field Weakening

Advances in Electrical and Computer Engineering, 2011
The paper describes sensorless speed controlled continuous Direct Torque Control (DTC) Induction Motor (IM) drive in the field weakening regime. Drive comprises an inner torque loop and an outer speed loop.
MATIC, P., VUKOSAVIC, S. N.
doaj   +1 more source

Design and Implementation of a Speed-Loop-Periodic-Controller-Based Fault-Tolerant SPMSM Drive System

Energies, 2019
This paper proposes a speed-loop periodic controller design for fault-tolerant surface permanent magnet synchronous motor (SPMSM) drive systems. Faulty conditions, including an open insulated-gate bipolar transistor (IGBT), a short-circuited IGBT, or a ...
Tian-Hua Liu, Muhammad Syahril Mubarok, Muhammad Ridwan, Suwarno   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Field programmable gate array–based servo control integrated chip for a six-axis articulated robot manipulator

Advances in Mechanical Engineering, 2016
The objective of this article is to build a field programmable gate array–based six-axis servo control integrated chip which can integrate the function of a motion trajectory planning and the function of six position/speed/current servo controllers into ...
Ying-Shieh Kung, Jin-Mu Lin, Yu-Jen Chen, Hsin-Hung Chou   +3 more
doaj   +1 more source

Processor In the Loop implementation of two stages Backstepping control strategy for Permanent Magnet Synchronous Motor based load torque observer [PDF]

EPJ Web of Conferences
This work deals with Backstepping control strategy for permanent magnet synchronous motor drive, using load torque observer. The proposed study uses a modified motor model with new variables, dynamic separation and Luenberger load torque observer.
El Haissouf Mohammed, El Haroussi Mustapha, Ba-Razzouk Abdellfattah, Bensaid Mounir   +3 more
doaj   +1 more source