Results 61 to 70 of about 15,659 (313)

Design of a RISC processor using VHDL [PDF]

open access: yes, 2003
This paper describes the design and implementation of a Reduced Instruction Set Computer (RISC) processor using a hardware description language, VHDL. The design is based on simple Programmable Integrated Circuit (PIC) instruction set and standard 8-bit ...
Ali, Mohd. Sholihin
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Implementation of a Prototype-Based Parkinson’s Disease Detection System Using a RISC-V Processor

open access: yesEngineering Proceedings
In the wide range of human diseases, Parkinson’s disease (PD) has a high incidence, according to a recent survey by the World Health Organization (WHO). According to WHO records, this chronic disease has affected approximately 10 million people worldwide.
Krishna Dharavathu   +5 more
doaj   +1 more source

Design and FPGA Implementation of a Digital Signal Processor [PDF]

open access: yes, 2013
The project aims at designing a Digital Signal Processor with 32-bit ISA (Instruction Set Architecture) using Verilog HDL and the implementation of its components in FPGA (Field Programmable Gate Array).
Parveen, Arifa
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

DSP implementation of surround speaker virtualizer for sound bar systems

open access: yesTelfor Journal, 2017
This paper describes one solution for an implementation of the surround speaker virtualization module for a digital signal processor in a sound bar system.
N. Kaprocki   +3 more
doaj   +1 more source

Embedded ARM System for Volcano Monitoring in Remote Areas: Application to the Active Volcano on Deception Island (Antarctica)

open access: yesSensors, 2014
This paper describes the development of a multi-parameter system for monitoring volcanic activity. The system permits the remote access and the connection of several modules in a network.
Luis Miguel Peci   +5 more
doaj   +1 more source

Mini project : dual processor computation : presentation transcript

open access: yes, 2010
This is the transcript of a presentation and comes from the 2009/10 BEng in Digital Systems and Computer Engineering (course number 2ELE0065) from the University of Hertfordshire.
University of Hertfordshire, School of Electronic Communications and Electrical Engineering
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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