Results 91 to 100 of about 16,132 (297)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
internetowy Kwartalnik Antymonopolowy i RegulacyjnyW artykule przedstawiono zaga dnienia dotyczące udostępniania i powierzania danych osobowych do przetwarzania ze szczególnym uwzględnieniem regulacji turystycznych w czasie trwania pandemii.
Stanislaw Hady-Głowiak, Dominik Borek
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Asymptotic bounds for M X /G/1 processor sharing queues
, 2003 This paper analyzed the asymptotic bounds of anM=G=1 processor sharing queue with bulk arrivals.
Misra, Vishal +3 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
On Stochastic Bounds for Monotonic Processor Sharing Networks
, 2004 International audienceWe consider a network of processor sharing nodes with independent Poisson arrival processes. Nodes are coupled through their service capacity in that the speed of each node depends on the number of customers present at this and any ...
Bonald, Thomas, Proutière, Alexandre
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Privacy-aware blockchain for personal data sharing and tracking
Open Computer Science, 2019 Secure data distribution is critical for data accountability. Surveillance caused privacy breaching incidents have already questioned existing personal data collection techniques.
Onik Md Mehedi Hassan +3 more
doaj +1 more source
Randomized assignment of jobs to servers in heterogeneous clusters of shared servers for low delay
Stochastic Systems, 2016 We consider the problem of assignning jobs to servers in a multi-server system consisting of N parallel processor sharing servers, categorized into M (≪N) different types according to their processing capacities or speeds.
Arpan Mukhopadhyay +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source