Results 131 to 140 of about 85,062 (229)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Strengthening supply chains for pathogen genomic surveillance in Asia. [PDF]

open access: yesBMJ Glob Health
Stona AC   +33 more
europepmc   +1 more source

Interplay of Crystallization and Amorphous Spinodal Decomposition During Thermal Annealing of Organic Photoactive Layers

open access: yesAdvanced Science, EarlyView.
Phase‐Field simulations are carried out to elucidate nanomorphology formation mechanisms in organic photoactive layers under thermal annealing. The predicted bulk heterojunction structures are in excellent agreement with Scanning Electron Microscopy measurements.
Maxime Siber   +3 more
wiley   +1 more source

Organ retrieval and collection of health information for donation: The ORCHID dataset. [PDF]

open access: yesSci Data
Adam H   +9 more
europepmc   +1 more source

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing

open access: yesAdvanced Science, EarlyView.
The critical pore spacing—approximately twenty times the pore radius—required to minimize electric field coupling is determined via finite element analysis. A multi‐layered Al2O3/Au/Si3N4 nanopore structure fabricated by helium ion beam lithography is proposed, enabling quantitative analysis of the target analyte while mitigating inter‐pore crosstalk ...
Silu Feng   +5 more
wiley   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

open access: yesAdvanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

Leveraging Digital Advanced Manufacturing to Enable Polymer Electrolyte Fuel Cells With Ultrahigh Gravimetric Power Density

open access: yesAdvanced Energy Materials, EarlyView.
This study employs digital advanced manufacturing to develop lightweight, compact porous distributors as alternatives to conventional bipolar plates in PEM fuel cells. A graphene‐coated nickel foam achieves a power density of 1.52 W cm−2, while titanium‐based designs deliver lightweight solutions: an LPBF‐fabricated Gyroid lattice reaches 1.36 W cm−2 ...
Hadi Heidary   +9 more
wiley   +1 more source

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