Results 141 to 150 of about 289,430 (341)

Visible Light‐Promoted Esterification of Carboxylic Acids via Photoacid Generation Catalysis

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A novel, environmentally friendly photochemical method for the esterification of carboxylic acids with alcohols using arylazo sulfones as photoacid generators was developed. This approach avoids traditional acidic catalysts, purification did not require chromatography and the method proved effective under continuous flow conditions for enhanced ...
Valentina Benazzi   +7 more
wiley   +1 more source

Cost‐Effective Hierarchical Cobalt Nanostructured Laser‐Induced Graphene for Enhanced Uric Acid Detection

open access: yesAdvanced Sensor Research, EarlyView.
A one‐step electrochemical strategy is utilized to develop a flexible, enzyme‐free biosensor for the sensitive detection of uric acid (UA). The hierarchical cobalt nanostructures synergistically enhance the performance of the biosensor, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM−1 cm−2 and a low detection limit
Anju Joshi, Gymama Slaughter
wiley   +1 more source

Enhanced Oxygen Evolution Reaction Performance of Niobium–Cobalt Oxide Catalysts in Acidic and Alkaline Media

open access: yesAdvanced Sustainable Systems, EarlyView.
The electronic modulation of Nb‐doped Co3O4 catalyst showcases enhanced activity and extended stability for OER in both alkaline (1M KOH) and acidic (0.5M H2SO4) electrolytes. The higher activity emanated from the synergistic effect between the Nb5+ dopant and Co3O4.
Kassa Belay Ibrahim   +7 more
wiley   +1 more source

A CMTM6 Nanobody Overcomes EGFR‐TKI Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Overcoming EGFR‐TKI resistance remains a critical challenge in NSCLC treatment. This study identifies CMTM6 as a key regulator of EGFR stability and demonstrates that a novel anti‐CMTM6 nanobody disrupts the CMTM6‐EGFR interaction. Targeting CMTM6 restores EGFR degradation, suppresses tumor growth, and confers therapeutic benefit in both CDX and PDX ...
Lu Xia   +18 more
wiley   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

Donor heart and lung procurement: A consensus statement.

open access: yesThe Journal of Heart and Lung Transplantation, 2020
H. Copeland   +29 more
semanticscholar   +1 more source

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

open access: yesAdvanced Science, EarlyView.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou   +7 more
wiley   +1 more source

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