Results 111 to 120 of about 66,274 (284)

Missense Variants in the A Isoform of FGF13 as a Novel Cause of Paroxysmal Dyskinesia

Movement Disorders, EarlyView.
Abstract Background Pathogenic variants within the unique N‐terminal inactivation particle of FGF13 isoform A (FGF13A) have so far been associated only with an X‐linked dominant epileptic encephalopathy (DEE). Objective The aim was to expand the clinical and molecular spectrum of FGF13A‐related disorder.
Cyril Mignot, Matthildi Athina Papathanasiou Terzi, Claudia Ravelli, Elisabeth Bosch, Xueqin Lin, Adeline Trauffler, Roseline Caumes, Andrew E. Fry, Clementine Fort, Gaelle Gauthe, Regina Trollmann, Thomas Wirth, Mathieu Anheim, Aurélie Méneret, Emmanuel Roze, Jean‐Madeleine de Sainte Agathe, Hailan He, Eleni Panagiotakaki, Gaëtan Lesca, André Reis, Diane Doummar, Thomas Smol, Georgia Vasileiou   +22 more
wiley   +1 more source

Head and Neck Manifestations of Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review. [PDF]

, 2016
OBJECTIVE: To conduct the first and only systematic review of the existing literature on head and neck manifestations of eosinophilic granulomatosis with polyangiitis to guide clinical decision making for the otolaryngologist.
Basnyat, Shristi, Goldfarb, Jared M., Nyquist, Gurston G., Rabinowitz, Mindy R., Rosen, Marc R.   +4 more
core   +1 more source

No increased risk of spinal cerebrospinal fluid leak after spinal manipulative therapy: A retrospective cohort study

PM&R, EarlyView.
Abstract Background Spinal cerebrospinal fluid (CSF) leaks, a rare but debilitating condition, have been described following spinal manipulative therapy (SMT) in case reports. However, the nature of the potential association between SMT and CSF leak is uncertain, and symptoms such as neck pain or headache may reflect preexisting leaks rather than ...
Robert J. Trager, Collin M. Labak, Anthony N. Baumann, Tyler H. Snodgrass, Zachary A. Cupler   +4 more
wiley   +1 more source

Multimodal diagnostic tools and advanced data models for detection of prodromal Parkinson’s disease: a scoping review

BMC Medical Imaging
Background Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta.
Ibrahim Serag, Ahmed Y. Azzam, Amr K. Hassan, Rehab Adel Diab, Mohamed Diab, Mahmoud Tarek Hefnawy, Mohamed Ahmed Ali, Ahmed Negida   +7 more
doaj   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

Phytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli, Giovanni Roviello, Giorgia Magliocca, Emilia Esposito, Anna Pannaccione   +4 more
wiley   +1 more source

Imaging advances to detect non-motor prodromal markers of Parkinson’s disease and explore therapeutic translation opportunities

npj Parkinson's Disease
Parkinson’s disease (PD) is a progressive neurological disorder marked by late-emerging motor symptoms, but early non-motor signs like hyposmia and REM sleep behavior disorder may precede diagnosis by years.
Mathangi Palanivel, Krishna Kanta Ghosh, Madhav Mallam, Raghavan Bhuvanakantham, Parasuraman Padmanabhan, Kah-Leong Lim, Balázs Gulyás   +6 more
doaj   +1 more source

Estimating Cognitive Impairment in Bipolar Disorder: Should We Account for Premorbid IQ?

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Cognitive impairment estimations traditionally rely on the deviation of current cognitive performance from population norms (normative approach). Since bipolar disorder (BD) has been associated with above‐average premorbid cognitive functioning in some studies, this approach might underestimate the extent of cognitive impairment ...
Dimosthenis Tsapekos, Michail Kalfas, Rebecca Strawbridge, Samuel Swidzinski, Katherine E. Burdick, Allan H. Young   +5 more
wiley   +1 more source

Prediagnosis Insights Into Amyotrophic Lateral Sclerosis: Clinical Symptoms and Medication Use

Journal of Cachexia, Sarcopenia and Muscle
Background Amyotrophic lateral sclerosis (ALS) has a prolonged latency period, though its preclinical characteristics remain poorly understood. This study uses UK Biobank data to explore and compare ALS's pre‐diagnostic features, including symptoms and ...
Chunyang Pang, Wen Cao, Jiali Xie, Yaojia Li, Luyi Zhu, Huan Yu, Dongsheng Fan, Binbin Deng   +7 more
doaj   +1 more source

Prodromal Symptoms in Patients Presenting With Myocardial Infarction. [PDF]

Cureus, 2023
Sohail H, Ram J, Hulio AA, Ali S, Khan MN, Soomro NA, Asif M, Agha S, Saghir T, Sial JA.   +9 more
europepmc   +1 more source

Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to examine potential interactions between sex and diagnosis across a broad range of variables, to compare ...
Maria Serra‐Navarro, Maria Heilbronner, Brisa Solé, Roger Borràs, Anabel Martinez‐Arán, Kristina Adorjan, Alba Navarro‐Flores, Mojtaba Oraki Kohshour, Daniela Reich‐Erkelenz, Eva C. Schulte, Fanny Senner, Ion‐George Anghelescu, Volker Arolt, Bernhard T. Baune, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Christian Figge, Markus Jäger, Georg Juckel, Carsten Konrad, Jens Reimer, Eva Z. Reininghaus, Max Schmauß, Andrea Schmitt, Carsten Spitzer, Jens Wiltfang, Jörg Zimmermann, Sergi Papiol, Urs Heilbronner, Peter Falkai, Thomas G. Schulze, Eduard Vieta, Carla Torrent, Monika Budde, Silvia Amoretti   +35 more
wiley   +1 more source