Results 171 to 180 of about 66,274 (284)

Associations between sleep disturbance and cerebrospinal fluid Aβ, and shared proteomic signatures in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Sleep disturbance is increasingly recognized as a risk factor for Alzheimer's disease (AD), but longitudinal clinical evidence linking sleep behaviors to cerebrospinal fluid (CSF) amyloid beta (Aβ) dynamics and related proteomic signatures remains limited.
Tianbai Li, Meichen Liu, Peng Zhang, Song Li, Tao Qiu, Xinhui Qiu, Bo Sun, Huaibin Cai, Cong Liu, Junliang Yuan, Weidong Le, Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

Annals of Neurology, Volume 99, Issue 4, Page 844-856, April 2026.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios, Jiali Gao, Carol A.C. Coupland, Julia Hippisley Cox, Martin R. Turner, Alexander G. Thompson   +5 more
wiley   +1 more source

Intolerance of uncertainty, paranoia, and prodromal symptoms: Comparisons between a schizophrenia spectrum disorder, anxiety disorder and non-clinical sample. [PDF]

Psychol Psychother
Morriss J, Ellett L.
europepmc   +1 more source

Adherence to the Mediterranean and Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diets and Parkinson's Disease Incidence in Women: Results from the Prospective E3N Cohort

Annals of Neurology, Volume 99, Issue 4, Page 1014-1029, April 2026.
Objective The evidence regarding adherence to dietary patterns and Parkinson's disease (PD) risk is inconsistent. Because of the long prodromal PD phase, reverse causation represents a major threat to investigations of diet in relation to PD. We examined whether adherence to the Mediterranean (MED) and Mediterranean‐Dietary Approaches to Stop ...
Mariem Hajji‐Louati, Emmanuelle Correia, Pei‐Chen Lee, Fanny Artaud, Emmanuel Roze, Francesca Romana Mancini, Alexis Elbaz   +6 more
wiley   +1 more source

Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial. [PDF]

Nat Med
Goadsby PJ, Ailani J, Dodick DW, Starling AJ, Liu C, Liu Y, Yu SY, Smith JH, Brand-Schieber E, Trugman JM.   +9 more
europepmc   +1 more source

Speech Biomarkers From Smartphone Calls Track Progression in REM Sleep Behavior Disorder and Parkinson's Disease

Annals of Neurology, Volume 99, Issue 4, Page 935-948, April 2026.
Objective This 24‐month longitudinal study involving isolated rapid eye movement sleep behavior disorder (iRBD), early‐stage Parkinson's disease (PD), and matched healthy control subjects aimed to assess whether acoustic speech features from real‐world smartphone calls provide passive progressive biomarkers in synucleinopathies.
Michal Šimek, Tereza Tykalová, Michal Novotný, Vojtěch Illner, Tomáš Kouba, Martin Šubert, Pavel Sovka, Jan Švihlík, Evžen Růžička, Karel Šonka, Petr Dušek, Jan Rusz   +11 more
wiley   +1 more source

Prodromal symptoms of rheumatoid arthritis in a primary care database: variation by ethnicity and socioeconomic status. [PDF]

Rheumatology (Oxford)
d'Elia A, Baranskaya A, Haroon S, Hammond B, Adderley NJ, Nirantharakumar K, Chandan JS, Falahee M, Raza K.   +8 more
europepmc   +1 more source

Atypical Guillain‐Barré Syndrome Preceding Icteric Hepatitis A: A Diagnostic Challenge—A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Guillain–Barré syndrome (GBS) is an acute immune‐mediated neuropathy typically triggered by infections. Rarely, it may precede acute hepatitis A (HAV), creating diagnostic challenges. We report a 32‐year‐old male presenting with ascending weakness and tingling in limbs without initial hepatic symptoms.
Asem Afana, Ahmed H. Sharaf, Jana Omar, Ahmad Elkhazin, Hossam Salameh   +4 more
wiley   +1 more source

Catheter Ablation for Frequent Premature Ventricular Contractions or Paroxysmal Supraventricular Tachycardia With Vagal Bradycardia: A New Clinical Application of Superior Vena Cava–Aorta Ganglionated Plexus Modification

Clinical Cardiology, Volume 49, Issue 4, April 2026.
This study demonstrates that combined RFCA and right atrial Ao‐SVC GP ablation provides a one‐stop, innovative solution for patients with vagal bradycardia and concomitant tachyarrhythmias, significantly improving symptoms and reducing syncope. ABSTRACT Background Frequent premature ventricular contractions (PVCs) or paroxysmal supraventricular ...
Xinai Meng, Senlin Huang, Liwei He, Tian Liu, Yanjia Chen, Huahua Li, Xingfu Huang   +6 more
wiley   +1 more source

Age and sex differences in vasovagal syncope: triggers, clinical presentation, prodromal symptoms, and head-up tilt test results. [PDF]

Eur Heart J Open
Babaei M, Tajdini M, Bozorgi A, Sadeghian S, Taebi M, Tavolinejad H, Mahalleh M, Taheri H, Rader F, Boris JR, Fedorowski A.   +10 more
europepmc   +1 more source