Results 191 to 200 of about 66,274 (284)

Importance and Difficulty of Differentiating BMA-induced AFF Prodromal Symptoms from Hormonal Therapy-related Femoral Pain. [PDF]

open access: yesIntern Med, 2020
Ota S   +15 more
europepmc   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Non-paraneoplastic limbic encephalitis associated with NMDAR and VGKC antibodies [PDF]

open access: yes, 2010
Derfuss, Tobias   +4 more
core   +1 more source

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

open access: yesMedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang   +5 more
wiley   +1 more source

Intensity of Psychoactive Substance Use Affects the Occurrence of Prodromal Symptoms of Psychosis. [PDF]

open access: yesJ Clin Med
Więckiewicz G   +6 more
europepmc   +1 more source

Exposure to Antipsychotics in Youths at Clinical High Risk for Psychosis: Low VS High Doses and Their Relevance for Clinical Outcomes

open access: yesEarly Intervention in Psychiatry, Volume 20, Issue 4, April 2026.
ABSTRACT Introduction Predicting prognosis in subjects at Clinical High Risk for Psychosis (CHR‐P) is still challenging. In particular, there are some disregarded factors such as ongoing Antipsychotic (AP) treatment that potentially induce method errors and research bias.
Lorenzo Pelizza   +9 more
wiley   +1 more source

Astrocyte Proximity Protects Synapses From Human Amyloid‐Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 7, April 2026.
Alzheimer's disease (AD) is the most common cause of dementia, affecting over 35 million people worldwide. A key feature of AD is the loss of synapses—the connections between brain cells—which strongly correlates with cognitive decline. We sought to investigate the role of astrocytes in mouse organotypic cultures challenged with brain homogenate (BH ...
Francesco Gobbo   +11 more
wiley   +1 more source

Interictal and Ictal Cognitive Performance in Episodic and Chronic Migraine

open access: yesEuropean Journal of Neurology, Volume 33, Issue 4, April 2026.
Migraine is not only a pain disorder but a dynamic network disorder with measurable cognitive consequences. Interictally, working memory impairment was observed in episodic migraine, while chronic migraine showed broader deficits in attention and executive functions.
Esra Kochan Kizilkilic   +2 more
wiley   +1 more source

Low Sensitivity of Neuropsychological Scales Hinder Detection of Potential Benefit of Treatments in Alzheimer's Disease: A Position Paper

open access: yesEuropean Journal of Neurology, Volume 33, Issue 4, April 2026.
ABSTRACT Background Despite the advent of Disease Modifying Therapies (DMTs) for Alzheimer's Disease (AD), the approval and commercialization of anti‐amyloid monoclonal antibodies has been slow and contentious, particularly in Europe. The primary source of debate is the discrepancy between robust biological effects—namely, effective β‐amyloid clearance—
Simona Luzzi, Julie S. Snowden
wiley   +1 more source

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