Results 81 to 90 of about 23,537 (260)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The Uncertainty War: Applying Entrepreneurial Practices to Microbudgeting for Short Films
The following paper offers an analysis of the development process of “Roof Knocking” (2017), a studio short film set in Gaza, spoken entirely in Palestinian Arabic, produced in Estonia, with a given budget of €5,000 euros.
Sergio Salazar Cavazos
doaj
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
This article is focusing on a group acceptance sampling plan for the Kumaraswamy Bell–Rayleigh distribution based on truncated life tests. For a specified group, the mean ratio as a quality measure is being used to determine the minimum number of lots ...
Sadia Nadir +4 more
doaj +1 more source
DESIGNING OPTIMAL CROP REVENUE INSURANCE [PDF]
The optimal crop revenue insurance contract is designed from recent developments in the theory of insurance economics under incomplete markets. The message is two-fold. Firstly, when the indemnity schedule is contingent on individual price and individual
Mahul, Olivier, Wright, Brian D.
core +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
MAY THE PRO-POOR IMPACTS OF TRADE LIBERALIZATION VANISH BECAUSE OF IMPERFECT INFORMATION ? [PDF]
In this paper, we try to evaluate the change in welfare gains and their distribution due to trade liberalization when imperfect information is considered.
Boussard, Jean-Marc +4 more
core +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Securitization in crop insurance with soil classification
Securitization is an emerging alternative to transfer of insurance risk, especially in cases exceeding the capacity of reinsurance, thus extending the insurability of risks.
Daniel KOMADEL +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

