Results 41 to 50 of about 10,740,998 (244)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Online Product Quantization

open access: yes, 2018
Approximate nearest neighbor (ANN) search has achieved great success in many tasks. However, existing popular methods for ANN search, such as hashing and quantization methods, are designed for static databases only.
Tsang, Ivor W., Xu, Donna, Zhang, Ying
core   +1 more source

Developing key concepts for the design of hypertext for printed books [PDF]

open access: yes, 2009
In the modern world, computers and interactivity are becoming an ever-increasing phenomenon, but this means that the tactile appeal of the printed book is giving way to the increasing popularity of digital interactivity. This research explores how one of
Timpany, Claire
core   +2 more sources

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Design e Spazio Urbano. Il potere degli oggetti nella città

open access: yesNarrare i Gruppi, 2020
Design and Urban Space. The power of the objects in the city ----- Abstract --- The constant increase of the urbanization has led to the existence of new ways of conceiving the city, to improve it and transform it into increasingly livable spaces ...
Lucetta Petrini
doaj  

Product Integrals and Wilson loops [PDF]

open access: yes, 2001
Using product integrals we review the unambiguous mathematical representation of Wilson line and Wilson loop operators, including their behavior under gauge transformations and the non-abelian Stokes theorem.
Karp, Robert L
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Remelting the high-carbon ferrochrome dust in a direct current arc furnace (DCF)

open access: yesMetalurgija, 2020
The paper describes the results of pilot remelting of high-carbon ferrochrome dust in a 1.8 MVA DC arc furnace. Standard grades of high-carbon ferrochrome, such as FeCh800, FeCh850 and FeCh900, were obtained with the following furnace performance: chrome
O. Sariev   +5 more
doaj  

IMPROVEMENT OF THE ERGONOMIC FUNCTION – AN ESSENTIAL CONDITION FOR ENSURING KNITTED PRODUCTS QUALITY [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2018
The evaluation products quality in general and particularly in knitted fabrics starts with determining their most important quality characteristics as an initial step in the multicriterial analysis used to establish the optimum ratio between the ...
LUTIC Liliana
doaj  

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