Results 121 to 130 of about 2,735,014 (284)

P18 | Face-off: shark or pig? Molecular authentication of typical products made from shark stomach and intestines available on the Chinese market, purchased online

Italian Journal of Food Safety
Purpose. Accurate monitoring of the shark product supply chain plays a fundamental role in ensuring traceability, sustainability, and transparency for consumers.
Lara Tinacci
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

BAYESIAN APPROACH TO RISK ASSESSMENT IN KNOWLEDGE BASED AUTHENTICATION [PDF]

Knowledge is quantified according to [1] as expertise and skills acquired by a person, the theoretical understanding of a specific subject or facts and information with respect to a specific field or domain.
Dragos PALAGHITA, Bogdan ZURBAGIU
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

THE FUTURE OF HUMAN AUTHENTICITY: REDEFINING AUTHENTICITY AS A PREMIUM PRODUCT

EPRA International Journal of Multidisciplinary Research (IJMR)
The use of artificial intelligence in our lives has become incredibly common. We engage with AI-based content daily, whether it is through our social networks, schools, entertainment, jobs, or elsewhere. As technology advances, we should be wondering if humans will continue to place a premium on experiences based primarily on their own work and ...
Sugunapriya T, Sanjeev K
openaire   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Efficient Authentication Protocols of GSM [PDF]

, 2009
[[abstract]]Undoubtedly, GSM is the most important standard of the worldwide wireless communication in recent periods. The authentication protocol is the main component of the GSM architecture.
Chang, C. C. ; Lee, J. S. ; Chang, Y. F
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Ensuring Privacy of Biometric Factors in Multi-Factor Authentication Systems

, 2008
One of the inherent properties of biometrics is the ability to use unique features for identification and verification of users. The usable biometric features in humans are limited in number and they must be kept secret; if a biometric factor is ...
Wills, Gary B, Apampa, Kikelomo M, Argles, David, Zhang, Tian   +3 more
core   +1 more source