Results 121 to 130 of about 8,529,401 (324)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

The Effectiveness of Product Codes in Marketing

open access: yes, 2015
This paper points out the effectiveness of product codes specifically quick response (QR) codes and barcodes in the marketing field. With all the knowledge and technological developments that the 21st century reached, the research explores new concepts ...
Mostafa, Ahmad Adel
core   +1 more source

New Binary Quantum Codes Derived From One-Generator Quasi-Cyclic Codes

open access: yesIEEE Access, 2019
In this paper, we consider a family of one-generator quasi-cyclic (QC) codes and their applications in quantum codes construction. We give a sufficient condition for one-generator QC codes to be self-orthogonal with respect to the symplectic inner ...
Jingjie Lv, Ruihu Li, Junli Wang
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Nonlinear Product Codes and Their Low Complexity Iterative Decoding

open access: yes, 2010
This paper proposes encoding and decoding for nonlinear product codes and investigates the performance of nonlinear product codes. The proposed nonlinear product codes are constructed as N-dimensional product codes where the constituent codes are ...
Valdemar C. da Rocha, Jr.   +6 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

High performance short-block binary regular LDPC codes

open access: yesAlexandria Engineering Journal, 2018
LDPC code shows a good performance with long-block codes. However, certain channels are constrained to use short-block codes due to latency. Therefore, concatenated LDPC codes with iterative decoding is a good choice to get a good performance ...
Latifa Mostari, Abdelmalik Taleb-Ahmed
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Matrix-product codes over Fq

open access: yes, 2001
Codes C-1,...,C-M of length it over F-q and an M x N matrix A over F-q define a matrix-product code C = [C-1 (...) C-M] (.) A consisting of all matrix products [c(1) (...) c(M)] (.) A.
Norton, Graham H., Blackmore, Tim
core   +1 more source

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