Results 131 to 140 of about 1,705,902 (280)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Machine learning and design of experiments with an application to product innovation in the chemical industry. [PDF]
J Appl Stat, 2022 Arboretti R +9 more
europepmc +1 more source
Innovation, competition and incentives for R&D [PDF]
This paper analyses the relationship between past innovation output, competition, and future innovation input in a dynamic econometric setting. We distinguish two dimensions of competition that correspond to the concepts of product substitutability and ...
Arvanitis, Spyros +2 more
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
R&D, Firm Size, and Product Innovation Dynamics. [PDF]
This paper addresses a debated issue in the economics innovation literature, namely the existence of increasing return to R&D expenditures and sirm size on innovation output.
Giuseppe Espa +2 more
core +3 more sources
Research-Based Product Innovation to Address Critical Unmet Needs of Patients with Inflammatory Bowel Diseases. [PDF]
Inflamm Bowel Dis, 2021 Honig G +3 more
europepmc +1 more source
Determinants of product innovation in small firms: A Comparison Across Industries [PDF]
A plethora of studies has investigated the determinants of product innovation in small firms, suggesting product, firm, market and innovation process factors as its key drivers of success.
Jeroen de Jong, Patrick Vermeulen
core
Quality Management, Production Process, Innovation and Productivity
Open Access Journal of Waste Management & Xenobiotics, 2019 This paper aims to analyse quality management systems, production process, innovation and productivity of manufacturing firms. In order to obtain that, we have taken into account aspects such as product standardization, the use of quality management systems, the complexity of the production system and some con ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Research on the impact of managers' green environmental awareness and strategic intelligence on corporate green product innovation strategic performance. [PDF]
Ann Oper Res, 2021 Yang G, Liu B.
europepmc +1 more source