Results 81 to 90 of about 264,030 (261)

Edge k-Product Cordial Labeling of Trees

Mathematics
The concepts of k-product cordial labeling and edge product cordial labeling were introduced in 2012 and further explored by various researchers. Building on these ideas, we define a new concept called ‘edge k-product cordial labeling’ as follows: For a ...
Jenisha Jeganathan, Maged Z. Youssef, Jeya Daisy Kruz, Jeyanthi Pon, Wai-Chee Shiu, Ibrahim Al-Dayel   +5 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

On 1-Near Mean Cordial Labeling of the Strong Product of Two Paths: Characterization and a Verification Algorithm

Journal of Mathematics
The 1-Near mean cordial labeling is a variation of mean cordial labeling. Let G=V,E be a simple graph. A surjective function h:VG⟶0,1,2 satisfies a 1-Near mean cordial labeling if for each edge xy, the induced map:h∗xy=0;if hx+hy/2 is an integer1 ...
Ashraf Elrokh, Khalid A. Alsatami, Rehab Hamza   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Product-cordial index and friendly index of regular graphs [PDF]

Transactions on Combinatorics, 2012
Let $G=(V,E)$ be a connected simple graph. A labeling $f:V to Z_2$ induces two edge labelings $f^+, f^*: E to Z_2$ defined by $f^+(xy) = f(x)+f(y)$ and $f^*(xy) = f(x)f(y)$ for each $xy in E$. For $i in Z_2$, let $v_f(i) = |f^{-1}(i)|$, $e_{f^+}(i) = |(f^
Wai Chee Shiu, Kwong Harris
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Global trends in e-labeling: a comprehensive geographical perspective

Frontiers in Medicine
IntroductionThis study presents a comprehensive analysis of e-labeling adoption for medicinal products worldwide. Electronic Product Information (ePI) makes available the most up to date approved medicinal product information on an electronic platform ...
Agnès Dangy-Caye, Valentin Lebreton, Rebecca Lumsden, Sabine Faber, Ana Cavalli, Maria Lucia De Lucia, Sima Desai   +6 more
doaj   +1 more source