A Product Oriented Modelling Concept: Holons for systems synchronisation and interoperability [PDF]
, 2006 Nowadays, enterprises are confronted to growing needs for traceability, product genealogy and product life cycle management. To meet those needs, the enterprise and applications in the enterprise environment have to manage flows of information that ...
Baïna, Salah +2 more
core +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A multi-stage supply chain disruption mitigation strategy considering product life cycle during COVID-19. [PDF]
Environ Sci Pollut Res Int, 2022 Chen J, Wang H, Fu Y.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Application of product life cycle concept to private label management
Tržište, 2013 Private labels have recorded significant growth rates worldwide, becoming a serious threat to manufacturer brands. Development of private labels in many different product categories increased the complexity of their management.
Sandra Horvat
doaj
Bridging the Gap: The Critical Role of Regulatory Affairs and Clinical Affairs in the Total Product Life Cycle of Pathology Imaging Devices and Software. [PDF]
Front Med (Lausanne), 2021 Kearney SJ +7 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Furniture Product Eco-Design Based on Life Cycle Assessment
BioResourcesThis study aimed to quantify the environmental impacts associated with furniture products’ life cycle, and to explore Life Cycle Assessment’s role in eco-design. The goal was to overcome any misconception of focusing solely on materials innovation in eco-
Dongfang Yang +3 more
doaj
Multiproduct Competition, Learning by Doing and Price-Cost Margins over the Product Life Cycle: Evidence from the DRAM Industry [PDF]
In this study we specify and estimate a structural model of multiproduct firms for the semiconductor industry. In addition, we explicitly consider dynamics over the product life cycle.
Ralph Siebert
core
Technology Development and Product Life Cycle: The Case of Counter-pressure Casting in Bulgaria [PDF]
, 1989 This paper presents the second part of the case study developed at the Metals Technology Company, in Bulgaria, which created and is applying the new original Bulgarian technology of casting by counter-pressure.
Djarova, J., Nenov, I., Tonchev, T.
core