Results 131 to 140 of about 2,636,574 (342)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Product ecodesign and materials: current status and future prospects

open access: yes, 2007
The aim of this paper is to discuss the current status of ecodesign in the industry and its future implications for materials. There is today more and more focus on the environmental impacts of products during their whole life cycle.
Brissaud, Daniel   +2 more
core   +2 more sources

A Product Oriented Modelling Concept: Holons for systems synchronisation and interoperability [PDF]

open access: yes, 2006
Nowadays, enterprises are confronted to growing needs for traceability, product genealogy and product life cycle management. To meet those needs, the enterprise and applications in the enterprise environment have to manage flows of information that ...
Baïna, Salah   +2 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Furniture Product Eco-Design Based on Life Cycle Assessment

open access: yesBioResources
This study aimed to quantify the environmental impacts associated with furniture products’ life cycle, and to explore Life Cycle Assessment’s role in eco-design. The goal was to overcome any misconception of focusing solely on materials innovation in eco-
Dongfang Yang   +3 more
doaj  

Application of product life cycle concept to private label management

open access: yesTržište, 2013
Private labels have recorded significant growth rates worldwide, becoming a serious threat to manufacturer brands. Development of private labels in many different product categories increased the complexity of their management.
Sandra Horvat
doaj  

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